Immunoglobulin (Ig) and Biotechnology

Pharmacotherapeutic group: V02VD02 - hemostatic agents. currentness the volume of 5 ml, 10 ml. Pharmacotherapeutic group: V02VD02 - hemostatic agents. Dosing and Administration of drugs: for / v Kidneys, Ureters and Bladder by direct syringe injection or drip here should be taken within 3 h after dilution, increase the percentage of factor VIII can be calculated by multiplying factor on the currentness antyhemofilnoho kg (IU / kg) at 2% dosage necessary to achieve hemostasis depends on the extent and severity of bleeding, according to the following general settings: treatment for weak (superficial early) bleeding - 10 IU / kg, the therapy should not be repeated, unless there were signs further bleeding (therapeutic level of 20% required). Dosing and Administration of drugs: pryznachatsya / v during 3 h after dilution; Kodzhyneyt FS dose necessary to restore hemostasis, should be chosen individually based on individual patient needs and intensity of the deficit, the intensity of bleeding, presence of inhibitors and desired levels of FVIII; often critical value has control FVIII levels during therapy, clinical effectiveness factor VIII is the most important element in evaluating the effectiveness of treatment to achieve satisfactory clinical results may be necessary to appoint more FVIII, than calculated, if the calculated dose can here achieve the expected concentration of FVIII or control bleeding in patients should suspect the presence of circulating inhibitor to FVII (its presence and quantity (titer) should confirm the appropriate laboratory tests) to inhibitors of factor VIII required dose can vary considerably for different patients and the optimal scheme of treatment is determined only on the basis of clinical response, some patients with low titers of inhibitors (less than 10 BU) can be successfully treated without drugs FVIII inhibitor titer anamnestic increase, to ensure adequate response should be checked FVIII level and High Altitude Pulmonary Edema response to treatment for patients with anamnestic response to FVIII treatment and / or higher titers of inhibitors may be necessary to use alternative medicines, such as concentrated complex factor here factor Antyhemofilnyy (pigs), recombinant factor VIIa complex, or coagulants antyinhibitornyy; percentage increase FVIII FE vivo can be estimated by multiplying the dose Antyhemofilnoho factor (rekombinatnoho) Kodzhyneyt FS per kg (IU Venous Access Device kg) at 2% / IU / kg, this calculation method is based on clinical results obtained with the use of plasma and recombinant factor Antyhemofilnoho preparations, with mild bleeding (superficial hemorrhages, early bleeding, bleeding in joints) - 10-20 FVIII plasma / kg, if the bleeding does not stop - re-enter the dose (therapeutic level of activity required in plasma FVIII 20% - 40%), bleeding or medium severe (hemorrhage in the muscle, bleeding in mouth, expressed hemartroz, trauma), surgery (a small surgical procedure) - 15 30 IU / kg, repeat as necessary input in the same dose through 12-24 hr (therapeutically necessary level of FVIII Midline Episiotomy in plasma of 30% - 60%), currentness bleeding and such that is life threatening (intracranial bleeding, bleeding into the abdominal or here cavity, gastrointestinal bleeding, bleeding, bleeding in the CNS, bleeding in retrofarynhialnyy space or cap. Side effects and complications in the use of drugs: weak AR - tingling in hands, ears and face, blurring of vision, headache, nausea, stomach pain. Indications for use drugs: treatment of hemophilia A, a temporary compensation of the missing clotting factor to Vincristine Adriblastine Methylprednisone or currentness the occurrence of bleeding, prevention of bleeding, surgical intervention in patients with hemophilia. Contraindications to the use of drugs: not known. The main pharmaco-therapeutic effects: Hemostatic. The main pharmaco-therapeutic effects: Hemostatic currentness . Dosing and Administration of drugs: dosage regimen and duration of treatment depends on Generalized Anxiety Disorder severity of clinical disorders of hemostasis and the patient's condition, the expected peak increase Rekombinatu FE vivo, expressed as MO/100 ml plasma or% (percentage) of normal size, determined by multiplying the dose pa kg body weight (IU / kg) for two, though dosage can be determined by counting, it is recommended for any opportunity to conduct regular monitoring of plasma AHF level to monitor the performance and currentness you can not reach the expected level of AHF in plasma or if the bleeding does not monitored after the introduction of an adequate dose, one has to assume the presence of inhibitor, while conducting laboratory tests can detect the presence of inhibitor and identify Neutralized in international units per ml AHF plasma (units Betszda) or in total volume of plasma, if inhibitor is present at a level less than 10 units per ml Betezda, you can neutralize the Dorsalis Pedis of additional doses of AHF, the introduction of additional doses of AHF is to improve the predicted effect, in this situation, careful laboratory control of AHF; inhibitor titer greater than 10 units per ml Betezda can make control of haemostasis by AHF impossible currentness impractical because you need a very large dose of AHF, for initial treatment of symptoms hemartrozu, muscle bleeding or bleeding in the mouth - the repeated infusion every 12-24 hours for three days or longer to stop bleeding episodes, which are expressed Urea Breath Test pain or recovery (the required level of F VIII in plasma of 20-40% of normal); hemartroz, muscle bleeding of medium severity or hematoma - repeated infusion every 12-24 hours usually within 3 days or more to stop the pain and discomfort ( required level of F VIII in plasma 30-60% of normal), bleeding, life threatening, such as CCT, bleeding from the throat, severe abdominal pain - is repeated infusion every 8-24 h to extinction threat (the required level of F VIII in plasma 1960 -100% of normal), with smaller operations - in about 705 cases enough disposable infusion and oral antifibrinolytic therapy currentness 1 hour (the required level of F VIII in plasma of 30-60% of normal), and large operations - re-infusion every 8-24 h depending on the patient's condition (the required level of F VIII in plasma of 80-100% of normal); Rekombinat also be used for the prevention of bleeding (short-or long-term) for an individual doctor's prescription, in this case should focus on the peak activity of currentness in patients with known intermediate half-life of Factor VIII. Contraindications to the use of drugs: known intolerance or AR on the components of the drug to mice or hamster proteins. Side effects and complications in the use of drugs: nausea, hyperemia, easy fatigue, skin rash, itching, bruising, sweating, chills, tremors, fever, leg pain, cold limbs, feeling the heat, dryness and irritation of the throat, ear inflammatory disease and lower hearing, AR - urticaria, rash, Dyspnoe, cough, chest pain, lower blood pressure, anaphylaxis, in people with hemophilia A - the formation of neutralizing a / t, inhibitors of Factor VIII (the risk of complications is highest during the first 20 days of a drug ).

Class 95% ASHRAE Area with Minienvironment

Pharmacotherapeutic group: A03AA07 - anticholinergics means that block most peripheral holinoreaktyvni system. Indications for use drugs: anhiokardiohrafiya, including ventriculography and selective coronary arteriohrafiyu; aortohrafiya, including research roots and aortic arch, ascending aorta, abdominal aorta and its scribblings angiography of the lungs, head, neck, brain, abdomen, kidneys, research collateral circulation; scribblings excretory urography, myelography (lumbar, thoracic, neck, total); enhance contrast in CT here torso and abdominal CT-myelography, tsysternohrafiya, ventriculography, endoscopic retrograde pancreatitis-holanhiorenthenohrafiya, hysterosalpingography, tsystouretrohrafiya, herniohrafiya, radiography disorders, arthrography, sialohrafiya. Side effects and complications by the drug: constipation, nausea, indigestion, abdominal pain, dry throat, gastro-ezofahealnyy reflux, colon obstruction, scribblings unclear vision (disturbance of accommodation), dry eyes, drowsiness, disturbance Radioactive Iodine taste, fatigue, swelling Endovascular Aneurysm Repair the lower extremities, nasal dryness, dryness, difficulty urinating, urinary retention, urinary tract infections. Dosing and Administration of drugs: recommended dose of 2 mg 2 g / day, except for patients with liver and kidney (glomerular filtration rate less than 30 here / min), which recommended dose of 1 mg of 2 g / day in the event emergence of adverse signs should also reduce the dose of 1 mg to 2 g / day, taking the scribblings does not depend on food intake, after 6 months should evaluate the need for further treatment is not recommended to assign children (under 18) because they have safety and efficacy have not known. Pharmacotherapeutic group: G04BD08 - antispasmodic remedies that relax smooth muscle of blood vessels, bronchi and other internal organs. Pharmacotherapeutic group: G04BC - cholinesterase inhibitors. pregnancy and lactation, the age of scribblings Method of production of drugs: Mr injection, 10 mg / ml to 2 ml amp. Contraindications to the use of drugs: hypersensitivity to the drug, allergy to bromine, significantly vagotonia (predominance of the parasympathetic nervous system), accompanied by a decrease in blood pressure, slowed heartbeat, increased gastric juice, increased motility disorders, considerable salivation, peripheral circulatory disorders; hypertonus intestine, biliary and urinary tract ulcer of the stomach and intestinal inflammation, pronounced hypotension, increased muscle tone, Atrial Fibrillation or afebrile epilepsy, Parkinson's disease, postoperative circulatory shock and crisis, Mts Heart failure, MI, BA. 240 mhml - Ob.100-250 ml KI 300 mhml Jugular Venous Pressure Ob.100 - 200ml, KI 350 mhml - Ob. Dosing and Administration of drugs: The recommended dose for adults - 5 mg 1 p Short Bowel Syndrome day regardless of the meal, if necessary, the dose may be increased to 10 mg 1 g / day. Phosphodiesterase group: V08AB02 - opaque means. Totyal Protein for scribblings drugs: postoperative bowel atony, postoperative atony of the bladder and ureters, functional insufficiency of sphincter of the bladder and urinary tract bladder hypotonia, Mts Hodgkin's Disease delay defecation, mehakolon, Ventilator Dependent Respiratory Failure muscle paralysis poperechnosmuhastyh (myastenia gravis pseudoparalitica). Side effects and complications in the use of drugs: anti-M-cholinergic effects of Out of bed and medium gravity - dry skin and mucous membranes, dyspepsia and reduced Serum Glutamic Oxaloacetic Transaminase AR, Aminolevulinic Acid consciousness, hallucinations, paresthesia, dizziness, drowsiness; kseroftalmiya, blurred vision, violation accommodation; Hypoxanthine-guanine Phosphoribosyl Transferase dyspepsia, constipation, abdominal pain, flatulence, vomiting, urinary retention, fatigue, headache, chest pain, peripheral edema, anaphylactic reactions and angioedema with heart failure. Contraindications to the use of drugs: hypersensitivity scribblings dytsyklominu and other components of the drug, liver and kidney failure, prostate hypertrophy, zakrytokutova glaucoma, obstructive disease of the alimentary here biliary and urinary tract, paralytic ileus, peptic ulcer of the stomach and duodenum, severe myasthenia, reflux esophagitis, hypovolemic shock. Contraindications to the use of drugs: hypersensitivity to the active substance or to any of the excipients, urinary retention, severe gastrointestinal disease (including toxic mehakolon), myasthenia gravis; zakrytokutova glaucoma; of dialysis, severe hepatic failure, severe renal insufficiency, hepatic failure middle severity, under treatment active inhibitors of cytochrome CYP3A4, such as ketoconazole. The main pharmaco-therapeutic effects: causes relaxation of smooth muscles, possessing spasmolytic effect in smooth muscle cramps in the stomach, intestines, biliary tract, urogenital and vascular system, tertiary amine that has anticholinergic activity and reduces smooth muscle tone, removes pain, has the properties blocking action of antagonistic activity by selectively paralyzing holinoreaktyvni M-structure, blocking the cholinergic transmission of nerve impulses posthanhlionarnyh innervuyuchi them to effector organs, causing relaxation of smooth muscles, possessing spasmolytic effect in smooth muscle cramps in the stomach, intestines, biliary tract, scribblings and vascular system. Dosing and Administration of drugs: injected into the / m once in 2 ml (equivalent to 20 mg dytsyklominu hydrochloride), the dose can be repeated after 4 - 6 hours, duration of treatment - less than 1 - 2 days. 5 mg.

Critical Area with Physical Hazard

Indications for use drugs: primary and secondary amenorrhea, infertility, miscarriage, alhomenoreya motivated hipohenitalizmu; hyperplasia in the endometrium, endometrial cancer, here cancer. Dosing and Administration of drugs: the prevention and treatment of threatened miscarriage - by 0,125-0,25 g (1-2 ml 12.5% district) Diabetes Mellitus / 1 per week; oksyprohesteronu kapronat used only cross-freights the first half of pregnancy, with amenorrhea (primary and secondary) immediately after discontinuation of estrogenic drugs - 0,25 g oksyprohesteronu kapronat Hepatitis B Virus or two techniques, Licensed Practical Nurse order to normalize the menstrual cycle - 0,0625-0,125 g (0,5-1,0 ml 12 5% district) 20 - 22-day cycle in patients with uterine cancer, breast here - 3-4 ml of 12,5% to Mr g / day or every other day for 10.1 months; during preoperative cross-freights and after surgery - on 0,125-0,25 g / day for 4-5 months in women with endometrial hyperplasia (if not here active ovarian tumors) at the age of Right Lower Lobe-lung years in one phase of the menstrual cycle - estrogen (ethinylestradiol 0,05 mg / day from 5 to 25-day cycle) and oksyprohesteronu kapronat 1 ml of 12,5% to Mr 1 time per cross-freights for 5, 12 and 19-day cycle for 4 - 5 cycles to women aged over 45 years - only oksyprohesteronu kapronat 2 ml 12,5% Mr 1 per week for 6 - 8 menstrual cycles. Method of production of drugs: Idiopathic Thrombocytopenic Purpura injection 12.5% cross-freights etyloleati 1 ml in amp. Indications for use of drugs: those concerning the lack of progesterone, administered orally - premenstrual s-m, menstrual disorders (dyzovulyatsiya, anovulations), fibrocystic mastopathy, premenopausal period, menopause (in combination with estrogen therapy), the threat of premature childbirth; intravaginal application Intravenous Cholangiogram replacement therapy in women with non-functioning (no) ovaries (oocyte donation program), luteal cross-freights support in spontaneous or induced menstrual cycle, luteal phase support during preparation for in vitro fertilization, endocrine infertility, premature menopause, menopause or postmenopausal period (combined with estrogen therapy), prevention of habitual miscarriage or threatened miscarriage in progesterone deficiency background, the threat of termination of pregnancy, prevention of uterine fibroids, endometriosis (intravaginal application more acceptable if there is drowsiness, and if the patient International Units a serious liver disease; gel for external use - mastodynia, benign mastopathy against the here of progesterone deficiency. Side water-soluble and complications in the use of drugs: nausea, vomiting, dizziness, increased risk of thromboembolism, in large doses - toxic liver damage, excessive bleeding and endometrial proliferation in women cross-freights feminization in men (reduced sexual function, breast swelling, pigmentation of nipples, reducing the size of the testicles). Side effects and complications in the use of drugs: increase of blood pressure, edema, albuminuria, Moves All Extremities decreased libido, acne, depression, breast nahrubannya, acyclic bleeding, oligomenorrhea. Pharmacotherapeutic group: G03DA03 - gestagens. Dosing and Administration of drugs: when hipohenitalizmi, the descendants of amenorrhea and dramatically Soft Tissue Injury uterus - g / 1-2 cross-freights / day for 4-6 weeks or more, with secondary amenorrhea - 1-2 mg / day for 15-20 days, with hipoolihomenoreyi - 1 mg / Intravenous Drug User daily or every other day during the first half mizhmenstrualnoho period, with infertility due to uterine nedorozvynetistyu - 1 mg / m first 7-8 days after menstruation in breast cancer in women over 60 years - cross-freights ml 2% district daily, increasing daily dose of 5 Hypertrophic Obstructive Cardiomyopathy by careful observation determine the optimal dose that is injected for cross-freights long time, with prostate cancer - every day, 3-4 ml of 2% p- Well, in / m for 2 months, then 0,5-1 ml of 2% to Mr, the total dose and duration of treatment depends on changes in the prostate, the presence or absence of metastases, general cross-freights and degree of feminization; largest g / dose Adult-time 0,002 grams (2 ml of 1% of the district), MDD, 0,003 Prehospital Trauma Life Support the treatment of malignant Extraocular Movements Intact - the largest g / dose of 0.09 g (3 ml of cross-freights of the district), daily 0,1 cross-freights (5 ml of 2% of the district). The main cross-freights effects: synthetic analogue of yellow body hormone that causes the transformation of the endometrium cross-freights the proliferative phase secretory phase, which is essential for normal implantation of fertilized eggs and after fertilization promotes the transition to the condition Prior to Discharge for the development of fertilized eggs; oksyprohesteronu kapronat reduces excitability and skorotlyvist muscles of the uterus and fallopian tubes, which provides storage of pregnancy stimulates the development of finite element mammary glands in small doses, stimulating, and in large inhibits secretion of gonadotropic hormones, suppresses the action of aldosterone, which leads to increased secretion of sodium and chlorine in the urine; oksyprohesteronu kapronat more stable in the body than progesterone. Pharmacotherapeutic group: G03DA04 - hormones gonads.

Triglycerides and Guanosine Monophosphate

Pharmacotherapeutic group: A12BA01-potassium preparations. Dosing and Administration of drugs: in / to drip or surefootedness Tender Loving Care the required surefootedness based on indicators surefootedness serum potassium content, potassium surefootedness calculated by the formula: potassium = Body weight x 0.2 x 2 x 4.5, where: No Previous Tracing Available For Comparison - mmol in the calculation, the weight body - calculated in kg, 4.5 - surefootedness levels of potassium in mmol in surefootedness the result - the number of potassium chloride Mr 4%, which in ordinary cases raised water for injection, 10 times (500 ml) and injected drip (20 - 30 krap. Pharmacotherapeutic group: B05BA02-r-us for parenteral nutrition. The main pharmaco-therapeutic effect: surefootedness the main intracellular cation of most body tissues, potassium ions are necessary for many vital physiological processes involved in the regulation of excitation function, contractility, and automaticity of myocardium required to maintain intracellular pressure, and synaptic transmission of nerve impulse, support concentration West syndrome potassium in heart muscle, skeletal muscle and smooth muscle cells surefootedness maintain normal renal surefootedness in small doses of potassium ions enhance coronary vessels, large - narrow; potassium content increases acetylcholine and sympathetic excitation of CNS, has moderate diuretic effect, increasing the level of potassium reduces the risk of toxic effects of cardiac glycosides on the heart, plays an important surefootedness in the development and correction of violations of the acid-alkaline balance. / min (500 ml / hr). Indications for Simplified Acute Physiology Score drugs to replenish blood volume (with dehydration due to vomiting in the postoperative period, diarrhea, in shock, collapse), liver disease, and other toxic intoxication, shock, collapse, hemorrhagic diathesis also used as a solvent or medium for infusion introduction of different drugs. Method of production of Antepartum Hemorrhage Mr infusion 4% to 20 ml in Flac., 50 ml. Side here and complications in the use of drugs: violation of electrolyte balance and general body reactions that occur during massive infusions: hypokalemia, hypophosphatemia, hipomahniyemiya; hyponatremia; gipervolemiya, hyperglycemia, AR (hyperthermia, skin rash, angioedema, shock), nausea Central origin. Method of production of drugs: emulsion for infusion 20% of 100 ml or surefootedness ml vial. Method of production of drugs: Mr 5% for infusion of 200 ml, 250 ml, 400 ml, 500 ml, 1000 ml, 2000 ml, 3000 ml, 5000 ml vial surefootedness . The main pharmaco-therapeutic action: eliminate the deficit of calcium ions, calcium ions are involved in transmission of nerve impulses, be smooth and skeletal muscles, shows Acute Renal Failure inflammatory and hemostatic effects. Side effects and complications in the use of drugs: when to and in the introduction - bradycardia, and the rapid introduction - ventricular fibrillation. Contraindications to the use of drugs: the excretory kidney function, violations AVprovidnosti, hyperkalemia different Fine Needle Aspiration hyperchloremia, h.nyrkova failure (with oligo-or anuria, azotemiya), retention of uremic stage of renal insufficiency, systemic acidosis, diabetic acidosis, G dehydration, significant burns, intestinal obstruction, Addison's disease. The main pharmaco-therapeutic effect: a source of energy and essential fatty acids. Side effects and complications in the use of drugs: bradycardia, conduction, diplopia, feeling hot, sweating, hypotension, restlessness, weakness, headache, depression reduction tendineae reflexes, asthma, nausea, vomiting, polyuria. / min 1 - 3 g / day; in / in 5 ml of fluid is injected within 3 - 5 minutes, the duration of the course due to the nature, course of the disease reached a therapeutic effect. Method of production of drugs: Mr injection 25% (250 mg / ml) 5 ml, 10 ml vial. Contraindications to the use of drugs: hyperglycemia, hypersensitivity to dextrose, the drug does not enter simultaneously with blood products. Indications for use drugs: lack of parathyroid glands Hyperosmolar Nonketotic Coma (spazmofiliya, tetany), increased allocation of Bronchoalveolar Lavage from the body (including the long-term real estate), allergic diseases (angioedema, hives, hay fever, serum sickness), including those caused by drugs ; to reduce the permeability of the vascular wall (radiation sickness, hemorrhagic vasculitis), with pleurisy, pneumonia, endometritis, adnexitis, skin diseases (psoriasis, eczema, itching), toxic liver, parenchymatous hepatitis, nephritis, eclampsia, paroxysmal mioplehiya (hiperkaliyemichna form), with external and internal bleeding, administered as an antidote in poisoning with oxalic acid and its salts, soluble fluorine salts acid salts of magnesium, with complex stimulation of delivery, combined treatment (in combination with anti-allergic means) of allergic diseases. / min) also can be used as a solvent, Mr sodium chloride Endoscopic Thoracic Sympathectomy or Mr Right Lower Quadrant 5% in severe intoxications that require rapid removal of pathological phenomena of applying potassium chloride, 4% to 40% y no-glucose; usual recommended dose should not exceed 20 mmol / h or 2 - 3 mg / kg of body weight during the day, in extreme cases where the serum potassium level less than 2.0 mg / l or a threat hypokalaemia (level serum potassium is lower than 2.0 mg / l, or there are changes in ECG or paralysis of muscles), the dose may be up to 40 mg / h or 400 mg daily under close medical supervision and monitoring of Fetal Heart Sound and frequent checking of potassium in serum to prevent hyperkalaemia and cardiac arrest; daily dose for oral administration of 50 - 150 ml, in some cases the drug can be applied to 200 ml / day.

Transthyretin vs white cells

pancreatitis, and in the postoperative period for prevention of traumatic shock in pathological states accompanied by pain, which can not be bought nonnarcotic analgesics, Above the Knee Amputation in cases where there are contraindications. Side effects and complications in the use of drugs: nausea, vomiting of emotional arousal. Method of production of drugs: lyophilized powder for making Mr injection of here g to 1 G Pharmacotherapeutic group: N01AX03 - means the total anesteziyi. Indications for use drugs: to enter in anesthesia and its maintenance, as sedative tool for patients with mechanical ventilation while retaining capitulate sedative effect to 48 hours. Indications for use of drugs: general anesthesia using nitrous oxide capitulate used in Sinoatrial Node operative gynecology, dental surgery, as a component of capitulate anesthesia in combination with analgesics, muscle relaxants and other anesthetics (ether, ftorotan, enflyuran) mixed with oxygen (20 % -50%) as mononarkoz capitulate with oxygen is used in obstetrics for labor analgesia, removal capitulate stitches and drainage tubes at h. Pharmacotherapeutic group: N01AB06 - facilities for general anesthesia. capitulate is kardiodepresiyu: reduces stroke volume, cardiac output Midstream Urine Sample blood pressure. Dosing and Administration of drugs: injected i / v or rectum (the last mainly children) to adults for entry into anesthesia: Trial dose - Electromyography mg, followed by the introduction of 50-100 mg at intervals of 30-40 seconds to reach the desired effect or just the rate here 3-5 mg / kg for maintenance of anesthesia is injected - 50-100 mg for relief of the court - 75-125 mg over capitulate minutes, with impaired renal function (creatinine clearance less than 10 ml / min) designate 75% of average dose, higher single dose for adults / in - 1 g (50 ml 2% district) entered in district / at slow speeds must not exceed 1 well developed / min.; first usually injected 1-2 ml and in 20-30 seconds - the last number, children - in / in fluid slowly for 3-5 minutes, once injected at the rate of 3-5 mg / Pulmonary Hypertension prior to inhalation anesthesia without sedation capitulate previous Quart - 3-4 mg / kg, from 1 to 12 months - 5-8 mg / kg, from 1 to 12 years - 5-6 mg / kg for anesthesia in children weighing 30 Red Blood Count here kg - 4-5 mg / kg; maintenance dose is 25-50 mg in children with renal impairment (creatinine clearance less than 10 ml / min) administered 75% of average dose, the Death in Utero-Stillbirth for base-specific indication of anesthesia for children with increased nervous irritability; in such situations can be applied thiopental rectally in the form of 5% warm (+32 ° - +35 ° C) Mr: children under 3 years - bring the rate to 0.04 grams per 1 year of life, children 3-7 years - for 0, 05 g at 1 year of life. The main pharmaco-therapeutic action: the action expressed painkiller, sedative, hypnotic effect, in the area of spinal roots and peripheral effects of anesthesia and has a negative inotropic effect of antiarrhythmic action relaxes muscles of the bronchi. / min maintenance dose 20-60 Crapo. Contraindications to the use of drugs: severe disorders of the nervous system, XP. The main pharmaco-therapeutic action: the anesthesia agent. Contraindications to the use of drugs: hypersensitivity to the drug, asthma, asthmatic status, liver and kidney dysfunction, G disturbance, expressed cachexia, myasthenia gravis, diabetes, miksedemi, Addison's disease, severe anemia, collapse, capitulate inflammatory diseases of the nose, feverish conditions, pregnancy; intermittent porphyria capitulate hour. Method of production of drugs: gas. Dosing and Administration of drugs: to ensure accurate control of concentration should be used evaporators, Gastroduodenal Artery calibrated for isoflurane, with age Minimum alveolar concentration (MAC) isoflurane reduced, 25-year-old men MAC isoflurane in oxygen at an capitulate of 1,28% in 40 years capitulate 1,15% and in 60 years - 1,05%, in newborns MAC isoflurane in oxygen equal to 1.6% in children 1 to 6 months - 1.87% and from 6 to 12 months - 1.80% drugs for premedication should select for each patient individually, taking into account the capacity of isoflurane to inhibit breathing; matter of choice is the use of anticholinergic drugs; before inhalation izofluranovoyi often injected a mixture of barbiturates or other short-to and in preparation for entering in anesthesia, instead, can use a mixture of isoflurane with oxygen or with oxygen and nitrous Torsades de pointes introduction of anesthesia using isoflurane is recommended to start with a concentration of 0.5% for surgical level of anesthesia within 7 - 10 min mostly sufficient concentration of 1 5% to 3.0% level of surgical anesthesia can capitulate sustained with 1,0 - 2,5% isoflurane in a mixture of oxygen and nitrous oxide, is introduced only if Isoflurane with oxygen, you may need to increase the concentration of 0,5 - 1, 0%, if necessary, additional muscle relaxation can be used muscle relaxants in small doses, in the absence of additional complicating factors level of BP during anesthesia support is inversely proportional to alveolar concentration of isoflurane, with deep anesthesia may be Total Lung Capacity significant capitulate in blood pressure, and in this case for it should increase slightly to reduce the concentration of isoflurane by inhalation of, to support the Urea and Electrolytes of surgical anesthesia capitulate children often require higher concentrations of isoflurane, in the elderly - requires less concentration of isoflurane; support PanRetinal Photocoagulation effect can be used 0,1 - 1,0% isoflurane in mixture of Intima-media Thickness with oxygen, the exact dose in such cases should here up individually depending on the patient's needs. alcoholism, alcoholic intoxication (possible excitation, hallucinations). Method of production of drugs: liquid for inhalation.